Gouri
Hydrate & Restore
GOURI is the world's first fully solubilized liquid polycaprolactone (PCL) injectable, developed by DEXLEVO (Korea) using proprietary CESABP technology. Unlike traditional PCL microsphere fillers (such as Ellansé), GOURI contains no particles — it is a true liquid that spreads evenly throughout the subcutaneous tissue from just 5 injection points, stimulating collagen production across the entire face simultaneously. PCL is a well-established biodegradable biomaterial with FDA-approved applications in medical devices.
BEFORE
AFTER
How it works
Once injected, liquid PCL naturally diffuses throughout the subcutaneous tissue, forming a 3D matrix beneath the skin. This PCL scaffold activates fibroblasts to produce new collagen and elastin — improving firmness, elasticity, and skin quality across the entire face uniformly. As PCL biodegrades over 12+ months, the newly stimulated collagen remains. The liquid formulation ensures even distribution without focal lumping or irregularity — a significant advantage over particle-based biostimulators.
Who is it for?
Global facial anti-aging (laxity, fine lines, loss of firmness across the entire face); patients wanting whole-face collagen regeneration in a single quick treatment; those who prefer fewer injection points; those wanting long-lasting, natural-looking results; patients who have 'plateaued' on HA boosters.
Who is it not for?
Pregnancy or breastfeeding; active infection or inflammation; PCL allergy; patients wanting immediate volume (GOURI improves skin quality, not volume); avoid 1 month before/after COVID vaccination.
Session Time
20–30 min
Down Time
Minimal — mild swelling at injection sites 24–48 hrs
Results?
4–8 weeks
Peak Results
Month 3–6 (after series)
How long does it last?
12+ months
How many sessions?
3 sessions spaced 4 weeks apart; then 1–2 maintenance sessions every 6 months
Build Your Protocol
Your skin has more than one concern. Your protocol should too.
How is GOURI different from Rejuran or Juvelook?
Rejuran (PDRN) and Juvelook (PDLLA+HA) are targeted skin boosters injected across many points for localized improvement. GOURI is a whole-face collagen stimulator — injected at just 5 points and spreading naturally across the entire face. They work on different mechanisms and complement each other well. Many patients use GOURI for foundational whole-face collagen building and add Rejuran or Juvelook for targeted hydration.
Will I look different immediately after?
GOURI produces no immediate volumizing effect. You may notice mild swelling at the 5 injection points for 24–48 hours. Results develop gradually as collagen is stimulated over the following weeks — a more refreshed, firmer, and more luminous version of yourself.
Can GOURI be combined with other treatments?
Yes — GOURI works synergistically with skin boosters (Rejuran, Juvelook), energy devices (OligioX, Ultherapy), and neurotoxins. In Korean clinics, it is increasingly used as the 'foundation' treatment, followed by targeted refinement treatments. Allow 2 weeks spacing with energy-based devices.